{"product_id":"chemokine-protocols-138-methods-in-molecular-biology","title":"Chemokine Protocols: 138 (Methods in Molecular Biology)","description":"\u003cp\u003e\u003cb\u003eAuthor:\u003c\/b\u003e Proudfoot, Amanda E.I.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBrand:\u003c\/b\u003e Humana\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEdition:\u003c\/b\u003e 2000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBinding:\u003c\/b\u003e Hardcover\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNumber Of Pages:\u003c\/b\u003e 353\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRelease Date:\u003c\/b\u003e 13-04-2000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDetails:\u003c\/b\u003e The chemokines family of small proteins are involved in numerous b- logical processes ranging from hematopoiesis, angiogenesis, and basal l- kocyte trafficking to the extravasation and tissue infiltration of leukocytes in response to inflammatory agents, tissue damage, and bacterial or viral infection. Chemokines exert their effects through a family of seven G-protein coupled transmembrane receptors. Worldwide interest in the chemokine field surged dramatically early in 1996, with the finding that certain chemokine receptors were the elusive coreceptors, required along with CD4, for HIV infection. Today, though over 40 human chemokines have been described, the n- ber of chemokine receptors lags behind―only 17 human chemokine receptors have been identified so far. What has emerged over the years is that most chemokine receptors bind several distinct ligands, and indeed the majority of chemokines are able to bind to multiple chemokine receptors, explaining to some extent the apparent disparity in the numbers of chemokines and rec- tors. Yet in spite of the apparent redundancy in chemokine\/chemokine rec- tor interactions, it is clear that in vivo, spatial, temporal, and indeed cell- and tissue-specific expression of both chemokines and their receptors are imp- tant factors in determining the precise nature of cellular infiltrates in phy- ological and pathological processes.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEAN:\u003c\/b\u003e 9780896037229\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePackage Dimensions:\u003c\/b\u003e 9.2 x 6.2 x 1.0 inches\u003c\/p\u003e\u003cp\u003e\u003cb\u003eLanguages:\u003c\/b\u003e English\u003c\/p\u003e","brand":"Humana","offers":[{"title":"Default Title","offer_id":49032430420272,"sku":"DRG.DelhiBookStore_9780896037229","price":5059.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0690\/9968\/4144\/files\/humana-book-default-title-chemokine-protocols-138-methods-in-molecular-biology-38673629184304.jpg?v=1753009795","url":"https:\/\/www.retailmaharaj.com\/products\/chemokine-protocols-138-methods-in-molecular-biology","provider":"Retail Maharaj","version":"1.0","type":"link"}