Drug Metabolism and Transport: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology)
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Drug Metabolism and Transport: Molecular Methods and Mechanisms (Me...
Author: Lash, Lawrence H.
Brand: Humana
Edition: 2005 ed.
Binding: hardcover
Format: Illustrated
Number Of Pages: 388
Release Date: 24-09-2004
Details: A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.
EAN: 9781588293244
Package Dimensions: 9.3 x 6.2 x 1.2 inches
Languages: English
